Endocrine Abstracts

Introduction: Normal or elevated TSH level in the presence of elevated T4 is defined as ‘inappropriate TSH syndrome’. Two main clinical conditions that can lead that syndrome are TSH-secreting adenoma (TSHoma) and resistance to thyroid hormone (RTH). Making the correct diagnosis is crucial in order to decide the most appropriate treatment option. Herein we presented clinical and laboratory data of seven patients who were hospitalised for the differential d...

A 21-year old male with a 4 year history of tip 1 diabetes mellitus was admitted for diabetic ketoasidosis. The patient was on premixed insulin in two divided of 20 units. He had poor control of diabetes with no regular follow up. His height was 141 cm (3rd persentile), and weight was 36 kg (3rd percentile). These anthropometric findings demonstrated low-height for his age. His bone age was consisted with 16 years. Physical examination revealed moon face, hepatomegaly, short s...

Aim: Vitamin D deficiency is reported as a risk factor for the development of diabetes in several epidemiologic studies. In this study, we investigated the frequency of 25-OH vitamin D deficiency in type 2 diabetes and the relationship between 25-OH vitamin D deficiency and microvascular complications.Materials and methods: Retrospectively, medical records of 557 type 2 diabetic patients admitted to the Endocrinology Outpatient Clinic in January–Mar...

Case: A 30-year-old man with hypoparathyroidism has been treated with calcitriol and calcium for 2 years, admitted hospital with persisting diarrhea. An endoscopic operation is planned. But when he was waiting for this examination as outpatient condition, he had a convulsion and had been taken in hospital by parents. Initial laboratory analyses revealed that he was hypocalcemic (total calcium of 6 mg/dl) and parathormone (PTH) 8 pg/ml, phosphorus 5.7 mg/dl, and magnesium 2 mg/...

Introduction: Major factor that modulates the PTH secretion is serum Ca level. Paratyhyroid gland also receives direct autonomic innervation. To date, measurement of several hormones such as cortisol,prolactin, renin and aldosteron were found to be affected by changing the posture from recumbent to the upright position. In the present study, we aimed to investigate postural change of PTH in normal individuals and patients with primary hyperparathyroidism (PHPT).<p class="a...

Introduction: Adrenal failure due to tuberculosis is rarely seen nowadays. There are few reports in the literature suggesting that adrenal insufficiency may improve with anti-tuberculosis therapy during the active phase of the disease. Herein, we presented a case of reversible adrenal failure in a patient with active tuberculosis.Case report: A 50-years-old-female patient admitted to our clinics with the complaints of weakness and darkening of the skin. ...

Background: Differentiated thyroid cancer is the most frequent thyroid tumor. Combinations of follicular carcinoma and papillary carcinoma are seen. Functional pituitary adenoma coexisting with differentiated thyroid carcinoma was reported previously in literature. We report a 47-year-old women with three different synchronous endocrine tumors; papillary thyroid cancer, follicular thyroid cancer, and prolactinoma.Case: A 47-years-old female patient was a...

Introduction: Viruses and virus-induced lymphokines may have an important role in the pathogenesis of autoimmunity. The occurrence and significance of autoimmune manifestations after the administration of viral vaccines remain controversial. Herein we have represented a case who developed type 1 diabetes 1 month after vaccination for measles in military.Case: A 25-year-old male patient admitted to our clinics with the complaints of polyuria, poydipsia, a...

Introduction: Association between ankle-brachial index (ABI) and coronary, cerebral, and peripheral vessels involvement has been shown in different studies. The normal range of ABI is between 0.9 and 1.4. Values below 0.9 show peripheral vessel disease. An ABI more than 1.4 is characteristic for vascular rigidity. We aimed to investigate the ABI value in our type 2 diabetic patients and association of ABI with glycemic control.Materials and methods: This...

Background: Diabetic retinopathy (DR) is the leading cause of blindness in the world. Retinopathy and nephropathy can still progress in diabetics despite optimal metabolic control. The aim of the present study was to determine whether different degrees of DR (proliferative or non-proliferative) were associated with abnormally modulated hemostatic parameters in patients with type 1 DM.Method: 52 type 1 diabetic patients and 40 healthy controls were enroll...